Naked woman on spice
When asked why police believe she was under the influence of spice, Shell said, “I think it was the behavior more than anything.”
That's an odd statement to make considering the enormous range of effects that third-rate chem can have on someone. Manufacturers routinely lie about the ingredients of their mixes, and their mixes are universally shit.
These more severe adverse effects in contrast to use of marijuana are believed to stem from the fact that many of the synthetic cannabinoids are full agonists to the cannabinoid receptors, CB1R and CB2R, compared to THC which is only a partial agonist and thus not able to saturate and activate all of the receptor population no matter of dose and resulting concentration.
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Psychiatrists treating him have suggested that the lack of an antipsychotic chemical, similar to cannabidiol found in natural cannabis, may make synthetic cannabis more likely to induce psychosis than natural cannabis.
In other words, synth THC goes way, way, way overboard on its effect and leaves behind the natural chaperone chem bud has. To make things more fun, it's a pain in the ass to detect without serious equipment. The standard piss test wouldn't show a thing.
Diogenes of Sinope: "It is not that I am mad, it is only that my head is different from yours."
Arnold Judas Rimmer, BSC, SSC: "Better dead than smeg."
Arnold Judas Rimmer, BSC, SSC: "Better dead than smeg."