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The results, published in the journal Nature, showed the cow's antibodies could neutralise 20% of HIV strains within 42 days.
By 381 days, they could neutralise 96% of strains tested in the lab.
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It is thought the cow's "ruminant" digestive system which ferments grass in order to digest it is a Wild West of hostile bacteria. So the animals have developed the antibodies needed to keep them in check.
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"Unlike human antibodies, cattle antibodies are more likely to bear unique features and gain an edge over HIV."
Unusually for human antibodies, the broadly neutralising ones have a long and loopy structure. Cow antibodies are inherently more long and loopy.